Amide hydrogen-deuterium exchange: A fast tool for screening protein stabilities in chromatography

• Published in: LC GC North America Vol. JUN; pp. 96 - 101
• Main Authors: FOGLE, Jace L, FERNANDEZ, Erik J
• Format: Magazine Article Trade Publication Article
• Language: English
• Published: Duluth, MN Advanstar Communications 01.06.2006; MultiMedia Healthcare Inc
• Subjects: Adsorption; Amino acids; Analytical chemistry; Analytical, structural and metabolic biochemistry; Antibodies; Biological and medical sciences; Chemistry; Chromatographic methods and physical methods associated with chromatography; Chromatography; Exact sciences and technology; Fundamental and applied biological sciences. Psychology; General aspects, investigation methods; Hydrogen; Hydrophobic surfaces; Ions; Labeling; Molecular weight; NMR; Nuclear magnetic resonance; Other chromatographic methods; Proteins; Scientific imaging; Solvents; Enzyme; Coupled method; Isotope exchange; Chemical stability; HPLC chromatography; Serum albumin; Hydrogen Isotopes; Serum protein; Separation method; Analysis method; Basic protein; Glycosidases; Hydrolases; O-Glycosidases; Mass spectrometry; Lysozyme
• ISSN: 1527-5949; 1939-1889