Botulinum toxin versus sacral neuromodulation for idiopathic detrusor overactivity

Idiopathic detrusor overactivity (motory urge) negatively affects the live of patients. Conservative treatment is not always effective and has multiple side effects. Sacral neuromodulation is a second line therapy for the treatment of idiopatic detrusor overactivity. Over the last decade, botulinum...

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Bibliographic Details
Published inUrologe. Ausgabe A Vol. 51; no. 3; pp. 348 - 351
Main Authors Leicht, W, Hampel, C, Thüroff, J
Format Journal Article
LanguageGerman
English
Published Germany 01.03.2012
Subjects
Administration, Intravesical
Botulinum toxin
Botulinum Toxins, Type A - administration & dosage
Electric Stimulation Therapy - instrumentation
Electric Stimulation Therapy - methods
Electrodes, Implanted
Humans
Lumbosacral Plexus - physiopathology
Pelvic Floor - innervation
Self Care
Urethra - innervation
Urinary Bladder - innervation
Urinary Bladder, Overactive - physiopathology
Urinary Bladder, Overactive - therapy
Urinary Catheterization
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Summary:Idiopathic detrusor overactivity (motory urge) negatively affects the live of patients. Conservative treatment is not always effective and has multiple side effects. Sacral neuromodulation is a second line therapy for the treatment of idiopatic detrusor overactivity. Over the last decade, botulinum toxin injections have been increasingly used as alternative although there are only few randomized studies. Goal of this review is to compare efficiacy, safety and cost effectiveness of both methods.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:0340-2592
1433-0563
DOI:10.1007/s00120-012-2819-4