Risk of Cardiovascular Complications and Geriatric Syndromes Among Elderly Women

• Published in: Kardiologiia Vol. 57; no. 3; p. 58
• Main Authors: Larina, V N, Runikhina, N K, Bart, B Y, Chukaeva, I I, Karpenko, D G
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 01.03.2017
• Subjects: Absorptiometry, Photon; Age Factors; Aged; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - physiopathology; Chronic Disease; Female; Geriatric Assessment; Humans; Odds Ratio; Osteoporosis; Prevalence; Syndrome; geriatric syndrome; cognitive impairment; cardiovascular risk; elderly; women
• ISSN: 0022-9040
• DOI: 10.18565/cardio.2017.3.58-64

to assess the prevalence of some geriatric syndromes and their association with high risk of cardiovascular complications (RCVC) among elderly women. We examined 72 women aged 69-77 years with cardiovascular diseases. Examination included laboratory and echocardiography assessment, dual-energy X-ray absorptiometry, 6-min walk test, assessment of psycho-emotional status using Mini-mental State Examination (MMSE) questionnaire. Frailty was defined as three or more of the following: weight loss, low physical activity levels, MMSE less or equal 23 points, weakness (chair stand test>10 sec), history of multiple falls. Follow up was 7.3 (5.5-7.8) months. High CVR was found in 70.8% women: in 59.1% women aged 65-74 years and in 89.3% - aged more or equal 75 years, =0.006. Osteoporosis (OP) was found in 51.3% women aged 65-74 and in 90.5% - aged more or equal 75 years, =0.024; MMSE was 27 (24-28) vs 24 (20-26) points, respectively, =0.008. The geriatric syndrome of frailty was found in 13.6% women aged 65-74 and in 64.3% - aged more or equal 75 years. Frailty was associated with high CVR (odds ratio [R] 7.2, 95% confidence interval [CI] 1.5-34.2, =0.013), chronic kidney disease (CKD, R 18.9, 95%CI 5.2-20.2, <0.001), P (R 4.5, 95%CI 1.3-15.8, =0.019), history of myocardial infarction (MI, R 6.8, 95%CI 2.2-20.8, =0.001), greater age (R 6.0, 95%CI 2.1-17.5, =0.001). High CVR was prevalent among greater age women what could be explained by prevalence of chronic heart failure, atrial fibrillation, CKD. Prevalence of frailty was 13.6 and 64.3% among women aged 65-74 and more or equal 75years, respectively. It was significantly associated with high CVR, OP, PMI, CKD.