Gestational alloimmune liver disease: a case report

Gestational alloimmune liver disease, previously known as neonatal hemochromatosis, is characterized by severe liver disease in neonatal period, associated with intra and extrahepatic iron accumulation. It is postulated an alloimmune origin, which has opened new opportunities in the treatment and pr...

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Bibliographic Details
Published inArchivos argentinos de pediatría Vol. 114; no. 6; pp. e408 - e412
Main Authors Laliena Aznar, Sara, Martínez Redondo, Inés, Oliván Del Cacho, María J, Martínez Del Moral, María, Pinillos Pisón, Raquel
Format Journal Article
LanguageSpanish
Published Argentina 01.12.2016
Subjects
Female
Hemochromatosis - diagnosis
Humans
Infant, Newborn
Neonatal liver disease
Liver failure
Congenital alloimmune hepatitis
Hemochromatosis
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Summary:Gestational alloimmune liver disease, previously known as neonatal hemochromatosis, is characterized by severe liver disease in neonatal period, associated with intra and extrahepatic iron accumulation. It is postulated an alloimmune origin, which has opened new opportunities in the treatment and prevention during risk pregnancies, changing the prognosis of this pathology. We report the case of a newborn that presents early liver failure, with clinical and analytical features compatible with gestational alloimmune liver disease. Exchange transfusion was made and gamma globulins were given, with good clinical evolution.
Bibliography:ObjectType-Case Study-2
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ISSN:1668-3501
DOI:10.5546/aap.2016.e408