Rapid antibiotic susceptibility test in Clinical Microbiology

The most widely used antibiotic susceptibility testing methods in Clinical Microbiology are based on the phenotypic detection of antibiotic resistance by measuring bacterial growth in the presence of the antibiotic being tested. These conventional methods take typically 24hours to obtain results. A...

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Bibliographic Details
Published inEnfermedades infecciosas y microbiologia clinica Vol. 34; no. 1; p. 61
Main Authors March Rosselló, Gabriel Alberto, Bratos Pérez, Miguel Ángel
Format Journal Article
LanguageSpanish
Published Spain 01.01.2016
Subjects
Anti-Bacterial Agents - pharmacology
Drug Resistance, Microbial
Microbial Sensitivity Tests - methods
Direct antibiotic susceptibility test
Antibiograma rápido
Antibiograma directo
Rapid antibiotic susceptibility test
Sensibilidad
Susceptibility
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Summary:The most widely used antibiotic susceptibility testing methods in Clinical Microbiology are based on the phenotypic detection of antibiotic resistance by measuring bacterial growth in the presence of the antibiotic being tested. These conventional methods take typically 24hours to obtain results. A review is presented here of recently developed techniques for the rapid determination of antibiotic susceptibility. Data obtained with different methods such as molecular techniques, flow cytometry, chemiluminescence, mass spectrometry, commercial methods used in routine work, colorimetric methods, nephelometry, microarrays, microfluids, and methods based on cell disruption and sequencing, are analyzed and discussed in detail.
ISSN:1578-1852
DOI:10.1016/j.eimc.2014.11.014