Evaluation of Cutaneous Microcirculation at the Dorsum of the Hand within Different Age Groups - Implications for Wound Healing in Hand Surgery?

• Published in: Handchirurgie, Mikrochirurgie, plastische Chirurgie Vol. 47; no. 6; p. 384
• Main Authors: Forstmeier, V, Sorg, H, Kabbani, M, Herold, C, Altintas, M A, Krämer, R
• Format: Journal Article
• Language: German
• Published: Germany 01.12.2015
• Subjects: Adult; Aged; Aging - physiology; Blood Flow Velocity - physiology; Cohort Studies; Double-Blind Method; Female; Hand - surgery; Hemoglobinometry; Humans; Male; Microcirculation - physiology; Middle Aged; Oxygen - blood; Prospective Studies; Regional Blood Flow - physiology; Skin - blood supply; Young Adult
• ISSN: 1439-3980
• DOI: 10.1055/s-0035-1555868

Cutaneous microcirculation has shown to play a key role in wound healing. Although healing disorders are still one of the most common complications in hand surgery, there still exists a lack of scientific research on possible age-related changes in cutaneous microcirculation at the dorsum of hand. Cutaneous microcirculation at the dorsum of the hand differs significantly between different age groups. 53 healthy subjects were divided into 2 groups by age (Group A:<40 years, n=31 vs. Group B≥40 years, n=22). All subjects underwent measurement of the microcirculation at the dorsum of the hand with combined laser-Doppler and photo spectrometry. Cutaneous oxygen saturation was significantly higher in Group A than in Group B (A: 64.7±9.9% vs. B: 58.3±12.6%; p=0,044). In contrast, blood flow velocity was significantly higher in Group B (A: 43±19.6 AU vs. B: 56.7±21.1 AU; p=0.019). The hypothesis of this study was confirmed. This is the first study to show significant differences of cutaneous microcirculation at the dorsum of the hand within different age groups. Further clinical trials are needed in order to examine if delayed wound healing can be correlated to impaired cutaneous microcirculation at the dorsum of the hand.