Factors associated with TB/HIV coinfection: evidence from notification data in the State of Amazonas, Brazil, 2001-2012

• Published in: Cadernos de saúde pública Vol. 33; no. 5; p. e00019315
• Main Authors: Magno, Evela da Silva, Saraceni, Valeria, Souza, Alexandra Brito de, Magno, Regma da Silva, Saraiva, Maria das Graças Gomes, Bührer-Sékula, Samira
• Format: Journal Article
• Language: Portuguese
• Published: Brazil 12.06.2017
• Subjects: Adolescent; Adult; Brazil - epidemiology; Coinfection - epidemiology; Databases, Factual; Female; HIV Infections - diagnosis; HIV Infections - epidemiology; Humans; Male; Middle Aged; Prevalence; Socioeconomic Factors; Tuberculosis - diagnosis; Tuberculosis - epidemiology; Young Adult
• ISSN: 1678-4464
• DOI: 10.1590/0102-311X00019315

Tuberculosis (TB) in persons living with HIV (PLHIV) is the leading infectious cause of AIDS-related death. The aim of this study was to estimate the prevalence of TB/HIV coinfection, evaluate notification of the two diseases over time by probabilistic database linkage, and identify factors associated with AIDS and TB notifications. Prevalence of TB/HIV coinfection was 7.7%. The group of PLHIV with subsequent TB diagnosis was the most representative, despite available preventive measures. Underreporting of TB among AIDS cases was 35%, and 19.6% of TB cases could have been reported as AIDS. For AIDS cases with mention of TB, living in the state capital showed 75% greater odds of being reported to the Tuberculosis Notification System (SINAN-TB), and having died increased the odds of reporting by 40%. Of TB cases with mention of HIV, brown skin color, age 25 to 39 years, living in the state capital, and having evolved to death were associated with higher odds of reporting to the AIDS Notification System. Periodic linkage of these databases can be a powerful tool for programs to decrease underreporting.