Osteosarcoma of the mastoid process following radiation therapy of mucoepidermoid carcinoma of the parotid gland--a case report

Radiation therapy is frequently used method in treatment of the head and neck malignancies. Osteosarcoma is a rare complication of radiation therapy and usually occurs after a long latent period. We report the case of 75-year-old female with osteosarcoma of the mastoid process. Twelve years before p...

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Bibliographic Details
Published inCollegium antropologicum Vol. 36 Suppl 2; p. 223
Main Authors Brusić, Sofija Kukić, Pusić, Marin, Cvjetković, Niko, Karnjus, Ruzica, Candrlić, Barbara, Kukuljan, Melita, Kastelan, Zrinka Matana, Miletić, Damir
Format Journal Article
LanguageEnglish
Published Croatia 01.11.2012
Subjects
Aged
Bone Neoplasms - diagnosis
Bone Neoplasms - etiology
Carcinoma, Mucoepidermoid - radiotherapy
Female
Humans
Magnetic Resonance Imaging
Mastoid - pathology
Neoplasms, Second Primary
Osteosarcoma - diagnosis
Osteosarcoma - etiology
Parotid Neoplasms - radiotherapy
Tomography, X-Ray Computed
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Summary:Radiation therapy is frequently used method in treatment of the head and neck malignancies. Osteosarcoma is a rare complication of radiation therapy and usually occurs after a long latent period. We report the case of 75-year-old female with osteosarcoma of the mastoid process. Twelve years before presentation she received radiation therapy after total parotidectomy and radical neck dissection in treatment of mucoepidermoid carcinoma of the parotid gland. Diagnostic procedures included contrast-enhanced CT and MRI of the head and neck and HRCT of the temporal bone. The final diagnosis of the low grade osteosarcoma was confirmed by biopsy. Diagnostic criteria were fulfilled and the lesion was classified as a radiation induced osteosarcoma.
ISSN:0350-6134