Relationship between natal course and metabolic parameters during the peripartal period in cattle

• Published in: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere Vol. 41; no. 6; p. 353
• Main Authors: Albanat, W A, Hüller, A, Köller, G, Fürll, M, Einspanier, A, Gottschalk, J
• Format: Journal Article
• Language: German
• Published: Germany 2013
• Subjects: Animals; Animals, Newborn - blood; Case-Control Studies; Cattle - blood; Fatty Acids, Nonesterified - blood; Female; Hydrocortisone - blood; Insulin-Like Growth Factor I - metabolism; Peripartum Period - blood; Pregnancy; Stress, Physiological - physiology; cortisol; Cow; IGF-1; difficult birth; non-esterified fatty acids; normal birth; heifer
• ISSN: 1434-1220
• DOI: 10.1055/s-0038-1623197

To evaluate metabolic disorders in high-yielding cattle du- ring the peripartal period, the relationship between the course of the delivery and relevant metabolic parameters (insulin-like growth fac-tor 1 [IGF-1], cortisol and non-esterified fatty acids [NEFA]) were examined. A total of 28 heavily pregnant cows (13 primiparous and 15 multiparous) with normal and difficult natal courses, respectively, were included in the study. Serum IGF-1, NEFA and cortisol were analysed between day 14 ante partum (a. p.) and day 14 post partum (p. p.), IGF-1 and cortisol were also determined in the newborn calves. An elevated stress situation was present for all heifers primarily at birth, because their serum IGF-1 levels were lower (114 ± 11 vs 158 ± 28 ng/ml) while NEFA and cortisol values were higher (896 ± 76 vs 705 ± 58 µmol/l, p = 0.05; 6.51 ± 1.14 vs 4.67 ± 0.46 ng/ml, p = 0.039, respectively) than those of the cows. During the entire examination period, metabolic disorders could be found in animals with difficult birth, based on significantly lower IGF-1 values (p = 0.003; heifers: p < 0.001), significantly higher NEFA levels (at birth p = 0.05) and higher cortisol values compared to the animals with a normal birth. Similar to their mothers, newborn calves of heifers with dystocia had significantly higher cortisol (p = 0.003) at birth and lower IGF-1 levels (p = 0.002) p. p. compared to calves with a normal natal course. Identification and prevention of natal disorders in cattle is very important, especially with regard to animal welfare and economics. In this study, difficult natal courses were associated with altered blood serum concentrations of IGF-1, NEFA and cortisol, which consequently reflect an elevated stress situation during the peripartal period. Furthermore, with regard to these results, it can be concluded that heifers with dystocia are affected by an increased metabolic stress situation mainly during the antepartal period, while multiparous cows suffer from metabolic disorders primarily in the period after birth.