Preoperative intravenous iron as a strategy for blood saving in surgery for hip fracture

• Published in: Medicina clinica Vol. 141; no. 9; p. 371
• Main Authors: Blanco Rubio, Nieves, Llorens Eizaguerri, María, Seral García, Belén, Burillo Fuertes, Pilar, Ranera García, Miguel, Albareda Albareda, Jorge
• Format: Journal Article
• Language: Spanish
• Published: Spain 02.11.2013
• Subjects: Aged; Aged, 80 and over; Blood Loss, Surgical; Blood Transfusion - utilization; Case-Control Studies; Cross Infection - epidemiology; Cross Infection - prevention & control; Drug Evaluation; Erythrocyte Transfusion - utilization; Erythropoiesis - drug effects; Female; Femoral Neck Fractures - surgery; Ferric Compounds - administration & dosage; Ferric Compounds - pharmacology; Ferric Compounds - therapeutic use; Glucaric Acid - administration & dosage; Glucaric Acid - pharmacology; Glucaric Acid - therapeutic use; Hip Fractures - surgery; Humans; Infusions, Intravenous; Male; Postoperative Complications - epidemiology; Postoperative Complications - prevention & control; Premedication; Preoperative Care; Retrospective Studies; Surgical Wound Infection - epidemiology; Surgical Wound Infection - prevention & control; Hierro intravenoso; Fractura de cadera; Hip fracture; Transfusion; Intravenous iron; Transfusión
• ISSN: 1578-8989
• DOI: 10.1016/j.medcli.2012.09.029

To determine whether administration of intravenous iron in a patient diagnosed with hip fracture reduces the need for blood transfusion. A retrospective observational case-control study was performed comparing a control group of 63 patients diagnosed with hip fracture with another group of 57 patients treated with parenteral iron. Demographic, clinical condition/clinical record and hematometric differences of the case-control patients were described. We analyzed the morbidity (post-surgical infection) and mortality rate. SPSS(®) was used for statistical studies. Being statistically significant, after the administration of intravenous iron sucrose, the need of blood transfusion was reduced in the case group, as well as the quantity of concentrates required (1.37 vs 0.6). In the case group, there was a statistically significant decreasing trend in hospital mortality rate (case group: 0.8%/control group: 8.3%). It was not been proven the relation between the decrease in nosocomial infection and the administration of intravenous iron The administration of intravenous iron sucrose in patients diagnosed with hip fracture before surgery could be effective blood saving measure in this type of trauma surgery. Furthermore, its use has been reliable without causing any side effects.