A Case of Invasive Pulmonary Mycosis (Rhizopus microspores) secondary to Hematological Disease

Pulmonary mucormycosis is most common in patients with hematologic malignancies and transplant recipients. This article describes a case of mucormycosis in the lungs secondary to a hematologic disorder with suspected lung cancer. Rhizopus (Rhizopus microspores) was detected by blood NGS and bronchoa...

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Bibliographic Details
Published inClinical laboratory (Heidelberg) Vol. 70; no. 8
Main Authors Yao, Xue X, Zhang, Ling, Sun, Si Y, Fu, Ai S, Liu, Tie J, Chen, Tong, Ge, Yan L
Format Journal Article
LanguageEnglish
Published Germany 01.08.2024
Subjects
Antifungal Agents - therapeutic use
Bronchoalveolar Lavage Fluid - microbiology
Hematologic Diseases - complications
Hematologic Diseases - diagnosis
Hematologic Diseases - microbiology
Humans
Invasive Fungal Infections - complications
Invasive Fungal Infections - diagnosis
Invasive Fungal Infections - drug therapy
Invasive Fungal Infections - microbiology
Lung Diseases, Fungal - complications
Lung Diseases, Fungal - diagnosis
Lung Diseases, Fungal - microbiology
Male
Middle Aged
Mucormycosis - complications
Mucormycosis - diagnosis
Rhizopus - isolation & purification
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Summary:Pulmonary mucormycosis is most common in patients with hematologic malignancies and transplant recipients. This article describes a case of mucormycosis in the lungs secondary to a hematologic disorder with suspected lung cancer. Rhizopus (Rhizopus microspores) was detected by blood NGS and bronchoalveolar lavage fluid NGS, and pulmonary mucormycosis was confirmed. Secondary to hematologic disease, pulmonary pneumonia, mycosis, and symptoms improved after comprehensive treatment. Clinical data and radiologic knowledge are combined to diagnose invasive pulmonary mycoses; early empirical medicine is very important.
ISSN:1433-6510
DOI:10.7754/Clin.Lab.2024.240331