Multiple cephalic deep granuloma annulare of children

• Published in: Annales de dermatologie et de vénéréologie Vol. 144; no. 10; pp. 612 - 616
• Main Authors: Bulinckx, A, Cambier, N, Wayllace Gaspar, L, Théate, I, Roquet-Gravy, P P, Bessis, D
• Format: Journal Article
• Language: French
• Published: France 01.10.2017
• Subjects: Child; Child, Preschool; Female; Granuloma Annulare - pathology; Head; Humans; Infant; Male; Granulome annulaire profond; Cephalic; Child; Deep granuloma annulare; Enfant; Céphalique
• ISSN: 0151-9638
• DOI: 10.1016/j.annder.2017.03.013

Deep granuloma annulare is a fairly rare variety of granuloma annulare. It is seen predominantly in children and mainly affects the anterior aspect of the legs and the top of the feet; cephalic presentation is rare. Below, we report three cases of deep granuloma annulare in children presenting solely at the cephalic extremity. Case 1: a six-year-old boy presented 7 cutaneous nodules measuring 1 to 2cm that were flesh-coloured, insensitive to palpation, of hard consistency and deeply attached. The lesions were grouped together on the anterior half of the left temporal fossa. While spontaneous regression of the three nodules was noted in the month following cutaneous biopsy, these nodules recurred a few months later. Case 2: a four-year-old girl with five deep cephalic nodules measuring around one centimetre and the colour of normal skin were seen on her right temporal fossa. The child was lost to follow-up after biopsy. Case 3: a four-month-old infant was presenting some 15 deep cutaneous nodules arranged in linear fashion on the forehead next to the left temporal fossa. These nodules regressed spontaneously one month after biopsy. In all three cases, histological examination confirmed the diagnosis of deep granuloma annulare. There have been few published cases of multiple, cephalic, deep granuloma annulare at a single site in children. The condition has an extensive differential diagnosis that includes malignant tumours; in addition, histological confirmation is normally essential. Treatment is not qualified and therapeutic extension with clinical monitoring alone may frequently be recommended.