Could gosereline acetate induce autoimmune-like hepatitis?

We report a case of acute icteric hepatitis attributed to goserelin acetate, occurred during prostate cancer treatment. Gosereline acetate could induce acute hepatitis, which characteristics are close to autoimmune hepatitis type I and may require hepatic monitoring.

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Bibliographic Details
Published inProgrès en urologie (Paris) Vol. 22; no. 10; p. 610
Main Authors Duburque, C, Bonnal, J-L, Gosset, P, Lucidarme, D
Format Journal Article
LanguageFrench
Published France 01.09.2012
Subjects
Antineoplastic Agents, Hormonal - adverse effects
Autoimmune Diseases - chemically induced
Chemical and Drug Induced Liver Injury - etiology
Chemical and Drug Induced Liver Injury - immunology
Goserelin - adverse effects
Humans
Male
Middle Aged
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Summary:We report a case of acute icteric hepatitis attributed to goserelin acetate, occurred during prostate cancer treatment. Gosereline acetate could induce acute hepatitis, which characteristics are close to autoimmune hepatitis type I and may require hepatic monitoring.
ISSN:1166-7087
DOI:10.1016/j.purol.2012.06.010