Highly sensitive graphene biosensors based on surface plasmon resonance

A surface plasmon resonance (SPR) based graphene biosensor is presented. It consists of a graphene sheet coated above a gold thin film, which has been proposed and experimentally fabricated recently [ChemPhysChem 11, 585 (2010)]. The biosensor uses attenuated total reflection (ATR) method to detect...

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Bibliographic Details
Published inOptics express Vol. 18; no. 14; pp. 14395 - 14400
Main Authors Wu, L, Chu, H S, Koh, W S, Li, E P
Format Journal Article
LanguageEnglish
Published United States 05.07.2010
Subjects
Biosensing Techniques - instrumentation
Graphite - chemistry
Surface Plasmon Resonance - instrumentation
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Summary:A surface plasmon resonance (SPR) based graphene biosensor is presented. It consists of a graphene sheet coated above a gold thin film, which has been proposed and experimentally fabricated recently [ChemPhysChem 11, 585 (2010)]. The biosensor uses attenuated total reflection (ATR) method to detect the refractive index change near the sensor surface, which is due to the adsorption of biomolecules. Our calculations show that the proposed graphene-on-gold SPR biosensor (with L graphene layers) is (1 + 0.025 L) x gamma (where gamma > 1) times more sensitive than the conventional gold thin film SPR biosensor. The improved sensitivity is due to increased adsorption of biomolecules on graphene (represented by the factor gamma) and the optical property of graphene.
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ISSN:1094-4087
DOI:10.1364/OE.18.014395