Detection of recombinations in tick-borne encephalitis virus by using computer analysis of viral genomes

Computer programs were used to search for tick-borne encephalitis (TBE) virus recombinants among the isolates whose complete nucleotide sequences are deposited in the GenBank database. The application of RDP, Chimaera, Maximum chi2, and TOPAL programs has revealed recombinant sites in a number of se...

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Bibliographic Details
Published inVoprosy virusologiĭ Vol. 56; no. 2; p. 14
Main Authors Dzhioev, Yu P, Paramonov, A I, Demina, T V, Kozlova, I V, Verkhozina, M M, Tkachev, S E, Pristavka, A A, Salovarova, V P, Zlobin, V I
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.03.2011
Subjects
Databases, Nucleic Acid
Encephalitis Viruses, Tick-Borne - genetics
Encephalitis, Tick-Borne - virology
Genome, Viral
Humans
Molecular Sequence Data
Recombination, Genetic
Siberia
Software - trends
Siberia
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Summary:Computer programs were used to search for tick-borne encephalitis (TBE) virus recombinants among the isolates whose complete nucleotide sequences are deposited in the GenBank database. The application of RDP, Chimaera, Maximum chi2, and TOPAL programs has revealed recombinant sites in a number of sequences, which indicates that TBE virus has recombinations and that the programs are suitable for their detection.
ISSN:0507-4088