Dynamics of biochemical markers of reparative fibrosis in uncomplicated course of myocardial infarction

Dynamics of biochemical markers of reparative fibrosis in patients with myocardial infarction (MI) with complicated course did not differ from that in the group of patients without complications. Development of complications was associated with elevation of blood serum content of glucosaminoglycans...

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Bibliographic Details
Published inKardiologiia Vol. 50; no. 12; p. 10
Main Authors Kim, L B, Putiatina, A N
Format Journal Article
LanguageRussian
Published Russia (Federation) 2010
Subjects
Adult
Aged
Biomarkers - blood
Disease Progression
Echocardiography
Electrocardiography
Female
Fibronectins - blood
Fibrosis - blood
Fibrosis - diagnosis
Follow-Up Studies
Glycosaminoglycans - blood
Humans
Hydroxyproline - blood
Male
Middle Aged
Myocardial Infarction - blood
Myocardial Infarction - diagnosis
Myocardial Infarction - physiopathology
Myocardium - pathology
Prognosis
Recovery of Function
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Summary:Dynamics of biochemical markers of reparative fibrosis in patients with myocardial infarction (MI) with complicated course did not differ from that in the group of patients without complications. Development of complications was associated with elevation of blood serum content of glucosaminoglycans in phase 3 of reparative fibrosis compared with group of patients without complications. This elevation was significant in the group of patients with rhythm disturbances. Statistically significant increase of total urinal oxyproline was found in patients with cardiac aneurism in phase 1 and in patients with cardiogenic shock in phase 3 of reparative fibrosis. These subject allow to speak about participation of reparative fibrosis in development of complications. Complications of myocardial infarction developed in patients aged 58 years and older.
ISSN:0022-9040