Small bowel transplantation: Report of a single case

Small bowel transplantation is associated with a patient survival at one and five years, of 80% and 63%, respectively. We report a 36 year-old female with short bowel syndrome, subjected to the first small bowel transplantation performed in Chile. A cadaveric gran was used. Immunosuppression was ach...

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Published inRevista medíca de Chile Vol. 137; no. 2; pp. 259 - 263
Main Authors Buckel G, Erwin, Ferrario B, Mario, Uribe M, Mario, González G, Gloria, Godoy L, Jorge, Fluxá G, Fernando, Quera P, Rodrigo, Codoceo R, Verner, Morales B, Jorge, Benavente M, David, Santander D, María Teresa, Herzog O, Cristina
Format Journal Article
LanguageSpanish
Published Chile 01.02.2009
Subjects
Adult
Chile
Female
Graft Rejection - prevention & control
Humans
Immunosuppressive Agents - therapeutic use
Intestine, Small - transplantation
Short Bowel Syndrome - immunology
Short Bowel Syndrome - surgery
Tacrolimus - therapeutic use
Chile
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Summary:Small bowel transplantation is associated with a patient survival at one and five years, of 80% and 63%, respectively. We report a 36 year-old female with short bowel syndrome, subjected to the first small bowel transplantation performed in Chile. A cadaveric gran was used. Immunosuppression was achieved by means of alemtuzumab, tacrolimus, sirolimus, micofenolate mofetil and steroids. Serial endoscopies and biopsies were performed during seven months after transplantation. The most important late complications were a drug induced renal failure, infections caused by opportunistic agents and a gastrointestinal bleeding probably induced by drugs. After 29 months of follow up, the patient is ambulatory, on oral diet only and with no evidence of graft rejection.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0034-9887