A new method of investigation of "child's" behavior (infant-mother attachment) of newborn rats

A new method of studying "child's" (maternal bonding) behavior of newborn rats was developed. The efficiency of the method was proved in estimation of dopaminergic control of the infant-mother attachment. Selective D2-antagonist clebopride applied in subthreshold for motor activity do...

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Bibliographic Details
Published inZurnal vyss̆ej nervnoj dejatelnosti imeni I P Pavlova Vol. 60; no. 2; p. 247
Main Authors Stovolosov, I S, Dubynin, V A, Kamenskiĭ, A A
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.03.2010
Subjects
Animals
Animals, Newborn
Behavior, Animal - drug effects
Benzamides - pharmacology
Dopamine Antagonists - pharmacology
Dopamine D2 Receptor Antagonists
Female
Male
Mother-Child Relations
Motor Activity - drug effects
Rats
Receptors, Dopamine D2 - physiology
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Summary:A new method of studying "child's" (maternal bonding) behavior of newborn rats was developed. The efficiency of the method was proved in estimation of dopaminergic control of the infant-mother attachment. Selective D2-antagonist clebopride applied in subthreshold for motor activity doses caused a decrease in aspiration of pups to be in contact with a dam. On the basis of features analyzed (latent periods and expression of various behavioral components), the integrated criterion for the estimation of "child's" reactions was suggested. Application of this criterion made it possible to neutralize high individual variability of the behavior typical of newborns.
ISSN:0044-4677