Granulomatous pulmonary involvement preceding diagnosis of Crohn disease: a pediatric case report

• Published in: Archives de pédiatrie : organe officiel de la Société française de pédiatrie Vol. 17; no. 9; pp. 1308 - 1312
• Main Authors: Roblin, E, Pecciarini, N, Yantren, H, Dubois, R, Hameury, F, Bellon, G, Bouvier, R, Lachaux, A
• Format: Journal Article
• Language: French
• Published: France 01.09.2010
• Subjects: Adolescent; Crohn Disease - complications; Crohn Disease - diagnosis; Crohn Disease - drug therapy; Diagnosis, Differential; Female; Granulomatous Disease, Chronic - diagnosis; Granulomatous Disease, Chronic - drug therapy; Granulomatous Disease, Chronic - etiology; Humans; Lung Diseases - diagnosis; Lung Diseases - drug therapy; Lung Diseases - etiology; Respiratory Function Tests; Severity of Illness Index; Time Factors; Treatment Outcome
• ISSN: 1769-664X
• DOI: 10.1016/j.arcped.2010.06.006

Crohn disease (CD) is a chronic bowel disorder that may affect many other organs such as the eyes, hepatobiliary system, skin, and joints. Pulmonary involvement in association with CD is a classic but uncommon manifestation. It can be primitive with granulomas or secondary to treatments. We report on the case of a teenager in whom the onset of CD was dominated by respiratory symptoms. Because of this presentation, we also suspected opportunistic infections such as tuberculosis and other granulomatous pulmonary diseases such as sarcoidosis or hypersensitivity pneumonitis.