Acute cyanosis after transcatheter balloon valvuloplasty: toxic methemoglobinemia due to local prilocaine use

Methemoglobinemia is characterized by varying degrees of cyanosis due to increased hemoglobin concentrations containing oxidized iron. Prilocaine is a widely used local anesthetic and can cause methemoglobinemia in infants even in therapeutic doses. We present two female infants (younger than 2 mont...

Full description

Saved in:
Bibliographic Details
Published inTürk Kardiyoloji Derneği arşivi Vol. 39; no. 1; pp. 64 - 67
Main Authors Ergül, Yakup, Nişli, Kemal, Kalkandelen, Selma, Dindar, Aygün
Format Journal Article
LanguageTurkish
Published Turkey 01.01.2011
Subjects
Anesthetics, Local - adverse effects
Ascorbic Acid - therapeutic use
Catheterization - adverse effects
Cyanosis - etiology
Female
Humans
Infant
Methemoglobinemia - chemically induced
Methemoglobinemia - diagnosis
Methemoglobinemia - drug therapy
Methylene Blue - therapeutic use
Prilocaine - adverse effects
Treatment Outcome
Online AccessGet full text

Cover

More Information
Summary:Methemoglobinemia is characterized by varying degrees of cyanosis due to increased hemoglobin concentrations containing oxidized iron. Prilocaine is a widely used local anesthetic and can cause methemoglobinemia in infants even in therapeutic doses. We present two female infants (younger than 2 months) who developed severe cyanosis after transcatheter pulmonary balloon valvuloplasty and were diagnosed with toxic methemoglobinemia. Both infants were anesthetized with local prilocaine application before balloon valvuloplasty. Methemoglobin levels of the patients were measured as 49.6% and 37.7%, respectively. Both were successfully treated with intravenous methylene blue and ascorbic acid.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Report-3
ObjectType-Case Study-4
ISSN:1016-5169