Hypothyroidism, dilated cardiomyopathy and nephrotic syndrome during pregnancy

Hypothyroidism during pregnancy is infrequent, but its presence is associated with maternal and fetal complications. We present the case of a young pregnant woman with no previous history of cardiovascular disease, who consulted for orthopnea, chest pain and edema in both legs. Laboratory tests demo...

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Bibliographic Details
Published inMedicina (Buenos Aires) Vol. 71; no. 1; pp. 45 - 48
Main Authors Saad, Ariel K, Lopez Soutric, Guillermo, Nowicky, Yael, Lerman, Jorge, Vazquez Blanco, Manuel
Format Journal Article
LanguageSpanish
Published Argentina 2011
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Summary:Hypothyroidism during pregnancy is infrequent, but its presence is associated with maternal and fetal complications. We present the case of a young pregnant woman with no previous history of cardiovascular disease, who consulted for orthopnea, chest pain and edema in both legs. Laboratory tests demonstrated a hypothyroid condition and a nephrotic syndrome with renal failure. The echo-Doppler exam showed a four chamber dilatation with systolic dysfunction. Treatment with intravenous levothyroxine improved her medical condition. We analyze the effects of thyroid hormone on the heart and vascular system and discuss the pathophysiologic mechanisms of heart failure during pregnancy.
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ISSN:0025-7680