Viral infection of herpes simplex, Epstein-Barr, varicela zoster, human papilloma, cytomegalovirus, or adenovirus are not related to sinonasal adenocarcinomas

Several types of virus have been implicated in the development of head and neck tumors. However, until now sinonasal adenocarcinomas (ACN) have not been studied. The aim of this study is to screen a series of ACN for the presence of a number of viruses known to play a role in cancer. Viral DNA seque...

Full description

Saved in:
Bibliographic Details
Published inActa otorrinolaringológica española Vol. 58; no. 7; p. 311
Main Authors Pérez Escuredo, Jhudit, Llorente, José Luis, Melón, Santiago, de Oña, María, García Martínez, Jorge, Alvarez Marcos, César, Hermsen, Mario
Format Journal Article
LanguageEnglish
Spanish
Published Spain 01.08.2007
Subjects
Adenocarcinoma - pathology
Adenocarcinoma - virology
Adenoviridae Infections - genetics
Aged
Aged, 80 and over
DNA, Viral - analysis
Epstein-Barr Virus Infections - genetics
Female
Herpes Simplex - genetics
Herpes Zoster - genetics
Humans
Male
Middle Aged
Papillomavirus Infections - genetics
Paranasal Sinus Neoplasms - pathology
Paranasal Sinus Neoplasms - virology
Polymerase Chain Reaction
Prevalence
Online AccessGet more information

Cover

More Information
Summary:Several types of virus have been implicated in the development of head and neck tumors. However, until now sinonasal adenocarcinomas (ACN) have not been studied. The aim of this study is to screen a series of ACN for the presence of a number of viruses known to play a role in cancer. Viral DNA sequences of herpes simplex virus, Epstein-Barr, varicela zoster, human papilloma, cytomegalovirus, and adenovirus were analysed by PCR in 37 primary ACN. Three tumors (8.1%) were positive for Epstein-Barr virus and 1 case (2.7%) for cytomegalovirus. Viral infections do not seem to play a role in the etiology of ACN.
ISSN:0001-6519
DOI:10.1016/S0001-6519(07)74934-8