Damage to erythrocyte membranes induced by high-intensity ultrasound

The effect of high-intensity ultrasound (11.2-54.2 W/cm2, frequency 36 kHz) on the structural and functional state of erythrocytes was investigated. It was shown that, at short-term action of the ultrasound (up to 1 min), the dose-dependent hemolysis of erythrocytes occurs. It was found that the exp...

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Bibliographic Details
Published inBiofizika Vol. 49; no. 5; p. 845
Main Authors Adzerikho, I E, Kozlova, N M, Antonovich, A N, Zubritskaia, G P, Slobozhanina, E I
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.09.2004
Subjects
Acetylcholinesterase - metabolism
Erythrocyte Membrane - chemistry
Erythrocyte Membrane - enzymology
Hemolysis
Humans
Lipid Bilayers - metabolism
Ultrasonics
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Summary:The effect of high-intensity ultrasound (11.2-54.2 W/cm2, frequency 36 kHz) on the structural and functional state of erythrocytes was investigated. It was shown that, at short-term action of the ultrasound (up to 1 min), the dose-dependent hemolysis of erythrocytes occurs. It was found that the exposure to ultrasound of high intensity (54.2 W/cm2) leads to the disruption of the structural state of erythrocyte membranes, which manifests itself in a change of microviscosity of the lipid bilayer of membranes and inhibition of the activity of the lipid-dependent membrane-bound enzyme acetylcholinesterase.
ISSN:0006-3029