Genetics contribution to the understanding of autism

Autism is a pervasive developmental disorder characterised by an impairment in social interaction and in communication, with unusual behaviour. Genetic factors are predominent in autism pathogenesis, in contrast with the environmental factors that would modulate the phenotype. The genetic polymorphi...

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Published inArchives de pédiatrie : organe officiel de la Société française de pédiatrie Vol. 12; no. 10; pp. 1509 - 1512
Main Authors Demonceau, N, Roubertie, A, Cheminal, R, Leydet, J, Rivier, F, Echenne, B
Format Journal Article
LanguageFrench
Published France 01.10.2005
Subjects
Autistic Disorder - genetics
Child
Genetic Predisposition to Disease
Humans
Phenotype
Polymorphism, Genetic
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Summary:Autism is a pervasive developmental disorder characterised by an impairment in social interaction and in communication, with unusual behaviour. Genetic factors are predominent in autism pathogenesis, in contrast with the environmental factors that would modulate the phenotype. The genetic polymorphism and the phenotypic heterogeneity make the autism a complex disorder to study. Genetic research on families with multiple affected children and biochemical mechanisms studies represent the sources for identifying the susceptibility genes in autism.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:0929-693X
DOI:10.1016/j.arcped.2005.06.007