HIV infection and cervical cancer: a note of caution for clinicians and health planners

• Published in: Medicina clínica Vol. 114; no. 7; p. 255
• Main Authors: López de Munain, J, Cámara, M M, Santamaría, J M, Baraia, J, Zubero, Z, Teira, R
• Format: Journal Article
• Language: Spanish
• Published: Spain 26.02.2000
• Subjects: Adult; Cervical Intraepithelial Neoplasia - complications; Cervical Intraepithelial Neoplasia - epidemiology; Cervical Intraepithelial Neoplasia - prevention & control; Cross-Sectional Studies; Female; HIV Infections - complications; HIV Infections - epidemiology; HIV Infections - prevention & control; Humans; Logistic Models; Risk Factors; Uterine Cervical Neoplasms - complications; Uterine Cervical Neoplasms - epidemiology; Uterine Cervical Neoplasms - prevention & control
• ISSN: 0025-7753
• DOI: 10.1016/S0025-7753(00)71262-0

To estimate the association between HIV infection and cervical intraepithelial neoplasia (CIN). Cross-sectional study based on data from 251 women from a Sexually Transmitted Diseases clinic. Patients with CIN were compared with those without CIN in terms of HIV infection and exposure to other risk factors, calculating the corresponding adjusted odds ratio (ORA) by logistic regression. HIV infection (ORA = 7.5; CI 95%: 2.5-22.1), having previous cytologies with cellular changes associated with human papillomavirus infection (ORA = 3.6; CI 95%: 1.3-10.2) and history of condylomas (ORA = 3.2; CI 95%: 1.2-8.4) were associated with CIN. The strong association observed between HIV and CIN, shows that it is necessary for health services planners and clinicians caring for HIV infected women to ensure that the latter receive the appropriate care to guarantee its early detection.