Pulmonary oxalosis with necrotizing pulmonary aspergillosis

Pulmonary oxalosis is a very rare pseudotumoral lesion; it is often secondary to an aspergillus infection. Oxalic acid (C(2)H(2)O(4)) is a mycotoxin released by Aspergillus niger and sometimes by several other fungi, including A flavus and A fumigatus. We report a case of a 69 year old man, with pre...

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Bibliographic Details
Published inAnnales de pathologie Vol. 22; no. 2; p. 121
Main Authors Khabir, Abdelmajid, Makni, Salwa, Ayadi, Lobna, Boudawara, Tahia, Frikha, Imed, Sahnoun, Youssef, Jlidi, Rachid
Format Journal Article
LanguageFrench
Published France 01.04.2002
Subjects
Aged
Aspergillosis - complications
Aspergillosis - pathology
Aspergillus fumigatus
Aspergillus niger
Humans
Lung Diseases, Fungal - complications
Lung Diseases, Fungal - pathology
Male
Necrosis
Oxalic Acid - analysis
Tuberculosis, Pulmonary - complications
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Summary:Pulmonary oxalosis is a very rare pseudotumoral lesion; it is often secondary to an aspergillus infection. Oxalic acid (C(2)H(2)O(4)) is a mycotoxin released by Aspergillus niger and sometimes by several other fungi, including A flavus and A fumigatus. We report a case of a 69 year old man, with previous history of pulmonary tuberculosis, followed for recurrent hemoptysis. On the chest radiography, the right upper lobe lung showed a cavitary lesion with thick and irregular walls and a dense material that suggested a pulmonary aspergilloma. Microscopically, it was a pulmonary oxalosis associated with chronic necrotising pulmonary aspergillosis. Our aim is to discuss the epidemiological characteristics, the diagnosis and the histogenesis of this unusual lesion.
ISSN:0242-6498