Extrapyramidal effects of antipsychotic drugs

Conventional antipsychotics have been used for many years to treat psychiatric and neurological disorders. Nevertheless, their effectiveness is often associated with a high incidence of side effects, especially extrapyramidal ones (EPS). With the entrance of the socalled atypical neuroleptics, this...

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Bibliographic Details
Published inNeurología (Barcelona, Spain) Vol. 18; no. 5; p. 262
Main Authors Kulisevsky, J, Otermin, P
Format Journal Article
LanguageSpanish
Published Spain 01.06.2003
Subjects
Akathisia, Drug-Induced - etiology
Antipsychotic Agents - adverse effects
Basal Ganglia Diseases - chemically induced
Humans
Psychotic Disorders - drug therapy
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Summary:Conventional antipsychotics have been used for many years to treat psychiatric and neurological disorders. Nevertheless, their effectiveness is often associated with a high incidence of side effects, especially extrapyramidal ones (EPS). With the entrance of the socalled atypical neuroleptics, this risk has been considerably, although not completely, reduced. Thus, clinicians should have good knowledge about the pharmacological characteristics of the newer anti-psychotics and their associated risk of worsening or developing motor disturbances. This article reviews these drugs, their pharmacological characteristics as well as the phenomenology of the extrapyramidal syndromes ans treatment of the EPS recommended.
ISSN:0213-4853