p53 mutants: the achilles' heel of human cancers?

Recent scientific discoveries have thrust mutants of the tumor suppressor protein p53 into the forefront of the war on cancer, and hold out eventual hope for a small molecule drug that will be useful in treating human cancers with mutant p53 protein.

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Bibliographic Details
Published inCell cycle (Georgetown, Tex.) Vol. 3; no. 8; pp. 1030 - 1034
Main Author Brachmann, Rainer K
Format Journal Article
LanguageEnglish
Published United States 01.08.2004
Subjects
Humans
Mutation - genetics
Neoplasms - genetics
Tumor Suppressor Protein p53 - genetics
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Summary:Recent scientific discoveries have thrust mutants of the tumor suppressor protein p53 into the forefront of the war on cancer, and hold out eventual hope for a small molecule drug that will be useful in treating human cancers with mutant p53 protein.
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ISSN:1551-4005