Primary osteoporosis risk factors in women from Córdoba, Argentina

• Published in: Medicina (Buenos Aires) Vol. 64; no. 5; pp. 400 - 406
• Main Authors: Balderramo, Domingo C, Ramacciotti, Constanza F, Douthat, Walter G
• Format: Journal Article
• Language: Spanish
• Published: Argentina 2004
• Subjects: Adult; Aged; Argentina - epidemiology; Body Mass Index; Bone Density; Case-Control Studies; Female; Fractures, Bone - epidemiology; Fractures, Bone - etiology; Humans; Logistic Models; Middle Aged; Osteoporosis - epidemiology; Osteoporosis - etiology; Postmenopause; Premenopause; Risk Factors; Argentina
• ISSN: 0025-7680

Risk factors for osteoporosis were evaluated in women from Cordoba, Argentina. Female patients that consulted about diagnosis or treatment of osteoporosis from January 2000 to June 2002 were included. Secondary osteoporosis patients were excluded. Participants were studied using standardized questionnaire, clinical examination, biochemical analysis, and dual-energy X-ray absorptiometry (DXA). According to lumbar spine DXA results and WHO criterion, we considered 2 groups: Osteoporosis (T score < -2.5 standard deviation, SD) and Control (T score > or = -2.5 SD). One hundred and fifty five women (Osteoporosis Group: 47; 108) were studied. In univariate analysis age, years from menopause, weight, smoking duration, estrogen replacement therapy duration, bilateral oophorectomy with hysterectomy, alkaline phosphatase levels, and Pouteau-Colles fractures were different between both groups. After multivariate analysis, including variables that were statistical different in univariate analysis, and considering osteoporosis as dependent variable, body weight (Odds Ratio, OR=0.92; CI 95% 0.87-0.98), alkaline phosphatase (OR=1.01; CI 95% 1.00-1.02), years from menopause (OR=1.12; CI 95% 1.05-1.21), and Pouteau-Colles fractures (OR=15.15; CI 95% 1.68-135.7) were independent risk factors for osteoporosis.