Oligoastrocytoma with signet-ring cell differentiation. A morphological, ultrastructural and immunohistochemical study

We present a case of a mixed glial tumor (oligoastrocytoma) with signet-ring cells. This cellular feature is a rare differentiation in glial tumors of the central nervous system. Histological, immunohistochemical and ultrastructural findings have been analyzed. Signet-ring cells showed intense expre...

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Bibliographic Details
Published inNeurocirugía (Asturias, Spain) Vol. 14; no. 1; pp. 46 - 51
Main Authors Ramos, D, Cerdá-Nicolás, M, López-Ginés, C, Roldán, P, Molla, J, Pérez-Bacete, M, Talamantes, F, Barberá, J, Llombart-Bosch, A
Format Journal Article
LanguageSpanish
Published Spain 01.02.2003
Subjects
Adult
Astrocytoma - pathology
Astrocytoma - ultrastructure
Brain Neoplasms - pathology
Brain Neoplasms - ultrastructure
Carcinoma, Signet Ring Cell - pathology
Carcinoma, Signet Ring Cell - ultrastructure
Female
Humans
Immunohistochemistry
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Summary:We present a case of a mixed glial tumor (oligoastrocytoma) with signet-ring cells. This cellular feature is a rare differentiation in glial tumors of the central nervous system. Histological, immunohistochemical and ultrastructural findings have been analyzed. Signet-ring cells showed intense expression with GFAP, S-100 and vimentin. A differential diagnosis with other primary brain tumors and cerebral metástases with signet-ring cell differentiation was discussed.
Bibliography:ObjectType-Article-2
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ISSN:1130-1473