Autogenous tarsus transplant as spacer for treatment of lower lid retraction in Grave's disease

• Published in: Klinische Monatsblatter fur Augenheilkunde Vol. 225; no. 8; p. 708
• Main Authors: Schittkowski, M P, Fichter, N, Guthoff, R F
• Format: Journal Article
• Language: German
• Published: Germany 01.08.2008
• Subjects: Adult; Aged; Eyelid Diseases - diagnosis; Eyelid Diseases - surgery; Female; Graves Ophthalmopathy - surgery; Humans; Male; Meibomian Glands - transplantation; Middle Aged; Ophthalmologic Surgical Procedures - methods; Surgery, Plastic - methods; Transplantation, Autologous - methods
• ISSN: 1439-3999
• DOI: 10.1055/s-2008-1027500

Lower lid retraction in dysthyroid orbitopathy is of less functional concern than optic neuropathy or diplopia in central positions of gaze. However, it may lead to incomplete lid closure resulting in corneal exposure. Patients often suffer from aesthetic impairment. A retrospective analysis of 13 consecutive patients treated for lower lid retraction due to Grave's Disease between 2005 and 2007 was undertaken. In spite of regular ophthalmological examinations, specific attention was directed to measurement of the lid fissure width and scleral show for quantification of lower lid retraction. OPERATION: The lower lid is everted and the conjunctiva is opened horizontally underneath the tarsal edge. Lower lid retractors are disinserted and dissected until the lower lid might be elevated in symmetry to the fellow eye. This procedure is continued until 1 mm overcorrection is gained. A free tarsal transplant is harvested from the ipsilateral upper lid tarsus. At least 4 mm vertical tarsus have to be left. Tarsus is sutured with absorbable material. In the 13 patients operated upon (9 women, 4 men) aged 23 - 67 years, scleral show was preoperative 2.7 mm (mean) and postoperative 0.1 mm. Lid fissure width was preoperative 13 mm (10 - 16 mm) and immediately postoperative 10.3 mm (7 - 13). 6 months postoperative the lid-elevating effect was reduced by 0.5 mm in maximum in the 9 patients available for control. The lid closure deficit, which was present in 7 patients before, could be corrected completely in 5 and diminished to 1 mm in 2 patients. Using this particular technique, functional and aesthetical satisfying results are obtained. The main advantages are renunciation of allogen, xenogeny or synthetic material with its possible risks of slow-virus infection and/or extrusion. Further studies are necessary to evaluate long-term results.