Metoclopramide and neonatal methaemoglobinemia

We report the case of a five-day-old newborn with cyanosis. After exclusion of pulmonary and cardiac illness, methaemoglobinemia was diagnosed. Cyanosis is the first symptom of methaemoglobinaemia. Numerous causes of methaemoglobinemia have been described, with congenital and acquired forms, which a...

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Bibliographic Details
Published inArchives de pédiatrie : organe officiel de la Société française de pédiatrie Vol. 12; no. 4; p. 438
Main Authors Mérieau, E, Suc, A L, Beau-Salinas, F, Norbert, K, Saliba, E, Cantagrel, S
Format Journal Article
LanguageFrench
Published France 01.04.2005
Subjects
Humans
Infant, Newborn
Male
Methemoglobinemia - chemically induced
Methemoglobinemia - diagnosis
Metoclopramide - adverse effects
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Summary:We report the case of a five-day-old newborn with cyanosis. After exclusion of pulmonary and cardiac illness, methaemoglobinemia was diagnosed. Cyanosis is the first symptom of methaemoglobinaemia. Numerous causes of methaemoglobinemia have been described, with congenital and acquired forms, which are the most frequent. We discuss here the clinical features, diagnosis, and treatment of acquired methaemoglobinaemia in newborns with special emphasis on forms secondary to metoclopramide toxicity.
ISSN:0929-693X
1769-664X
DOI:10.1016/j.arcped.2005.01.017