Renal oncocytoma: CT diagnostic criteria revisited

• Published in: Journal de radiologie Vol. 86; no. 12 Pt 1; pp. 1773 - 1782
• Main Authors: Eiss, D, Larousserie, F, Mejean, A, Ghouadni, M, Merran, S, Correas, J M, Hélénon, O
• Format: Journal Article
• Language: French
• Published: France 01.12.2005
• Subjects: Adenoma, Oxyphilic - diagnostic imaging; Adult; Aged; Aged, 80 and over; Female; Humans; Kidney Diseases - diagnostic imaging; Male; Middle Aged; Retrospective Studies; Tomography, X-Ray Computed
• ISSN: 0221-0363
• DOI: 10.1016/S0221-0363(05)81521-5

To redefine and evaluate the computed tomographic criteria for the diagnosis of renal oncocytoma (RO) for which renal sparing surgery should be preferred. Retrospective study of 57 patients with 69 RO. Macroscopic and histological correlation was obtained in all cases. A double blinded comparative study was made of 60 renal tumors (containing adenocarcinomas and oncocytomas) larger than 3 cm in diameter in order to evaluate the redefined CT diagnostic criteria. Among RO larger than 3 cm in diameter, 55% presented a sharply defined low attenuation scar on post-contrast scans at the tubular nephrographic phase, central or eccentric, with homogeneous attenuation throughout the remainder of the hypervascular tumor which was classified in 3 different groups. The use of our CT diagnostic criteria gave a statistically significant (p < 0.05) Kappa index of inter-observer concordance of 0.71 and a specificity of 96% for the diagnosis of RO. Our redefined computed tomographic criteria for the diagnosis of renal oncocytoma, eventually associated with renal biopsy, should increase the indications for renal sparing surgery for RO larger than 3 cm in diameter.