Comparison of oncostatin M cytokine levels in saliva and serum in periodontitis: a clinicobiochemical study

• Published in: Canadian Journal of Dental Hygiene Vol. 58; no. 3; pp. 155 - 160
• Main Authors: Sonkusle, Shweta, Singh, Varsha
• Format: Journal Article Trade Publication Article
• Language: English
• Published: Canada Canadian Dental Hygienists Association 01.10.2024; CJDH
• Subjects: Adult; Alveolar bone; Arteriosclerosis; Bleeding; Bone loss; Bone resorption; Cardiovascular diseases; Case-Control Studies; Chemokines; Chemotaxis; Ciliary neurotrophic factor; Cytokines; Dendritic cells; Dental plaque; Endothelial cells; Enzyme-Linked Immunosorbent Assay; Female; Gingival index; Glycoproteins; Gum disease; Humans; Interleukin 6; Investigations; Leukemia; Leukocytes (neutrophilic); Lymphocytes T; Macrophages; Male; Melanoma; Microbiomes; Middle Aged; Neurotrophic factors; Neutrophils; Oncostatin M - blood; Oncostatin M - metabolism; Original Research; Osteoclasts; Periodontitis - blood; Periodontitis - immunology; Periodontitis - metabolism; Plaque index; Rheumatoid arthritis; Saliva - chemistry; Saliva - immunology; Sample size; Wound healing; cytokine; saliva; oncostatin M; periodontitis; biomarker; serum; interleukin-6

Oncostatin M (OSM), a 28 kDa glycoprotein 130 pleiotropic cytokine belonging to the interleukin-6 (IL-6) family, is mainly produced by neutrophils, activated T cells, monocytes, and macrophages. In response to tissue injury, it may stimulate the production of IL-6 alone or act synergistically with I...