Mixed cryoglobulinemia associated with hepatitis C virus

We report six cases of essential mixed cryoglobulinemia associated with chronic liver disease and positive HCV markers, who showed several acute symptoms of vasculitis, arthralgias, neuropathy and glomerulonephritis. The presence in the serum and cryoprecipitates of anti HCV antibodies detected by t...

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Bibliographic Details
Published inRevista española de enfermedades digestivas Vol. 87; no. 1; p. 65
Main Authors De Diego Lorenzo, A, Bañares Cañizares, R, González-Asanza, C, Pérez Roldán, F, Casado Martín, M, Hernández-Albújar, A, Cos Arregui, E, Clemente Ricote, G
Format Journal Article
LanguageSpanish
Published Spain 01.01.1995
Subjects
Adult
Cryoglobulinemia - complications
Cryoglobulinemia - virology
Female
Hepatitis C - complications
Humans
Male
Middle Aged
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Summary:We report six cases of essential mixed cryoglobulinemia associated with chronic liver disease and positive HCV markers, who showed several acute symptoms of vasculitis, arthralgias, neuropathy and glomerulonephritis. The presence in the serum and cryoprecipitates of anti HCV antibodies detected by the second-generation ELISA (ELISA 2) and the of HCV RNA by PCR in the serum in all six cases, suggest an important role for this virus in the pathogenesis of mixed cryoglobulinemia.
ISSN:1130-0108