Structural properties of leukemic and normal lymphoid cells

DNA synthesis intensity and spectral and fluorescent properties of leucemic, PHA-induced and intact normal mouse spleen cells and of nuclei isolated from these cells were investigated. The cell electrophoretic mobility and DNA-protein interaction in the nuclei were studied. Similarity in cell and nu...

Full description

Saved in:
Bibliographic Details
Published inBiofizika Vol. 31; no. 4; p. 638
Main Authors Svirnovskiĭ, A I, Tsygankov, V G, Medved', I N, Shimanskaia, T V, Levin, V I
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.07.1986
Subjects
Animals
Cells, Cultured
DNA - biosynthesis
DNA, Neoplasm - biosynthesis
Fluorescent Dyes
Leukemia, Experimental - metabolism
Lymphocyte Activation
Lymphocytes - metabolism
Mice
Mice, Inbred C57BL
Spectrophotometry, Ultraviolet
Spleen - cytology
Spleen - metabolism
Online AccessGet more information

Cover

Abstract DNA synthesis intensity and spectral and fluorescent properties of leucemic, PHA-induced and intact normal mouse spleen cells and of nuclei isolated from these cells were investigated. The cell electrophoretic mobility and DNA-protein interaction in the nuclei were studied. Similarity in cell and nuclei fluorescence, fluorescence of the probe ANS conjugated with the cells, the electrophoretic mobility and tightness of DNA--protein interaction for leucemic and PHA--induced cells and also the similarity of the tightness of DNA--protein interaction for leucemic and normal intact cells were found inspite of the differences in DNA synthesis intensity and cell functional peculiarities.
AbstractList DNA synthesis intensity and spectral and fluorescent properties of leucemic, PHA-induced and intact normal mouse spleen cells and of nuclei isolated from these cells were investigated. The cell electrophoretic mobility and DNA-protein interaction in the nuclei were studied. Similarity in cell and nuclei fluorescence, fluorescence of the probe ANS conjugated with the cells, the electrophoretic mobility and tightness of DNA--protein interaction for leucemic and PHA--induced cells and also the similarity of the tightness of DNA--protein interaction for leucemic and normal intact cells were found inspite of the differences in DNA synthesis intensity and cell functional peculiarities.
Author Tsygankov, V G
Shimanskaia, T V
Medved', I N
Svirnovskiĭ, A I
Levin, V I
Author_xml – sequence: 1
  givenname: A I
  surname: Svirnovskiĭ
  fullname: Svirnovskiĭ, A I
– sequence: 2
  givenname: V G
  surname: Tsygankov
  fullname: Tsygankov, V G
– sequence: 3
  givenname: I N
  surname: Medved'
  fullname: Medved', I N
– sequence: 4
  givenname: T V
  surname: Shimanskaia
  fullname: Shimanskaia, T V
– sequence: 5
  givenname: V I
  surname: Levin
  fullname: Levin, V I
BackLink https://www.ncbi.nlm.nih.gov/pubmed/3756231$$D View this record in MEDLINE/PubMed
BookMark eNotj0tqwzAUALVISdM0RyjoAoanJ0u26KqE_iCQRdt1kOQnYiLbQrIXuX0LzWo2w8A8sNU4jbRiGwDQlQQ092xXSu9AgJYSBa7ZWjZKoxQb9vw158XPS7aRpzwlynNPhU-BR1ouNPSe27Hj45SHPyNeh3Se-o57irE8srtgY6HdjVv28_b6vf-oDsf3z_3LoUpCtnPVCRGECVI770B5bT22BK2pEXXjJDWOghK-9TWG4JSurekaVACNIkfK4JY9_XfT4gbqTin3g83X020CfwEcHkUd
ContentType Journal Article
DBID CGR
CUY
CVF
ECM
EIF
NPM
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
DatabaseTitleList MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod no_fulltext_linktorsrc
DocumentTitleAlternate Strukturnye svoĭstva leĭkoznykh i normal'nykh limfoidnykh kletok
ExternalDocumentID 3756231
Genre English Abstract
Journal Article
Comparative Study
GroupedDBID 642
ALMA_UNASSIGNED_HOLDINGS
CGR
CUY
CVF
ECM
EIF
NPM
ID FETCH-LOGICAL-p138t-d11f19f36bcb05c6ac28e08942267b3e7bef51c8c42ffb564a9d7250075ebe592
ISSN 0006-3029
IngestDate Fri Sep 17 22:46:19 EDT 2021
IsPeerReviewed true
IsScholarly true
Issue 4
Language Russian
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-p138t-d11f19f36bcb05c6ac28e08942267b3e7bef51c8c42ffb564a9d7250075ebe592
PMID 3756231
ParticipantIDs pubmed_primary_3756231
PublicationCentury 1900
PublicationDate 1986 Jul-Aug
PublicationDateYYYYMMDD 1986-07-01
PublicationDate_xml – month: 07
  year: 1986
  text: 1986 Jul-Aug
PublicationDecade 1980
PublicationPlace Russia (Federation)
PublicationPlace_xml – name: Russia (Federation)
PublicationTitle Biofizika
PublicationTitleAlternate Biofizika
PublicationYear 1986
SSID ssib010633212
ssib015893047
ssib005904684
ssib000992019
Score 1.283077
Snippet DNA synthesis intensity and spectral and fluorescent properties of leucemic, PHA-induced and intact normal mouse spleen cells and of nuclei isolated from these...
SourceID pubmed
SourceType Index Database
StartPage 638
SubjectTerms Animals
Cells, Cultured
DNA - biosynthesis
DNA, Neoplasm - biosynthesis
Fluorescent Dyes
Leukemia, Experimental - metabolism
Lymphocyte Activation
Lymphocytes - metabolism
Mice
Mice, Inbred C57BL
Spectrophotometry, Ultraviolet
Spleen - cytology
Spleen - metabolism
Title Structural properties of leukemic and normal lymphoid cells
URI https://www.ncbi.nlm.nih.gov/pubmed/3756231
Volume 31
hasFullText
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnZ3bS-NAFIcHLwi-LC6u7Loq8-BbyZK5JRl8Ei_Igr60gm-STGY0tCaltoX613vmYhNFWdeXUDKlTfIlJ79z5pwzCB1qBu-gkicREzyNuFEyyqSKIyo0uBtCMaptofDlVXJxzf_eiJt24URXXTIt_qind-tKvkIV9gFXWyX7H2SXPwo74DPwhS0Qhu2nGPdd81fXOGNsg-oT2x3Vyr-Rng1d1rsNi9dWlo56owWAa6qyZ2P1j68mcys4iqdquLTQ_Xk1qZu5XdIatObxqTcgy_jq4HFxl9fDZu6SZNvVuS51Obex09QZns4kz331AG_EYe4Tcwchsbb0xXdZssxLbe2nzZQLMYpgPxnp3Ce8YwwT37elA2L84Eiw1Kou8s_BN52ww8gqWk0za8yuXgVmJO02lhcSHP-2BBccX8Zoq-SIAJ0Wc99RNZzTJtoI__DGxXBSY7CFvgUfAR974N_RymS2jY5a2LiFjRuDX2BjgI09bPwCGzvYP9D1-dng5CIKK19EY8KyaVQSYog0LClUEQuV5IpmOs6kLXtOC6bTQhtBVKY4NaYQCc9lmYKYBf0HD6WQdAet1U2tfyKsZK5L-FrONeOlAfFBC5aZONWUg69NfqEdf663Y9_e5DZchN2PBn6jzfbe2EPrBp4mvQ_SbFocOCjPt4c1MA
link.rule.ids 786
linkProvider National Library of Medicine
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Structural+properties+of+leukemic+and+normal+lymphoid+cells&rft.jtitle=Biofizika&rft.au=Svirnovski%C4%AD%2C+A+I&rft.au=Tsygankov%2C+V+G&rft.au=Medved%27%2C+I+N&rft.au=Shimanskaia%2C+T+V&rft.date=1986-07-01&rft.issn=0006-3029&rft.volume=31&rft.issue=4&rft.spage=638&rft_id=info%3Apmid%2F3756231&rft_id=info%3Apmid%2F3756231&rft.externalDocID=3756231
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0006-3029&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0006-3029&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0006-3029&client=summon