Assessment of fetal maturity by measurement of the phospholipids in the amniotic fluid. Comparison of the results with the lecithin/sphingomyelin ratio

The authors explored the possibility of assessing fetal lung maturity by measuring the phospholipids in the amniotic fluid by the enzymatic technique of Takayama et al. [8]. The study was conducted on 41 pregnancies. The results obtained were evaluated comparatively with the lecithin/sphingomyelin r...

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Bibliographic Details
Published inAnnales de biologie clinique (Paris) Vol. 41; no. 3; p. 219
Main Authors Alegre, B, Bretó, M, Salvadó, J, Sendra, R, Gresa, M, Argudo, A
Format Journal Article
LanguageFrench
Published France 1983
Subjects
Amniotic Fluid - analysis
Female
Fetal Organ Maturity
Humans
Lung - embryology
Phosphatidylcholines - analysis
Phospholipids - analysis
Pregnancy
Pregnancy Trimester, Third
Sphingomyelins - analysis
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Summary:The authors explored the possibility of assessing fetal lung maturity by measuring the phospholipids in the amniotic fluid by the enzymatic technique of Takayama et al. [8]. The study was conducted on 41 pregnancies. The results obtained were evaluated comparatively with the lecithin/sphingomyelin ratio (L/S). The authors found that the L/S ratio can be used to determine fetal lung maturity in 93% of cases with 2/14 false maturities and 1/27 false immaturities. The assay of the phospholipids containing choline by the method of Takayama et al. [8] gives a much less precise assessment of fetal lung maturity: only 68% of the results were concordant; 5/14 false maturities and 8/27 false immaturities. These differences can be explained by the fact that the method of Takayama et al. [8] takes into account substances which are not related to process of fetal lung maturation.
ISSN:0003-3898