Pure alexia: presentation of three cases and review of the literature

• Published in: Revista de neurologiá Vol. 25; no. 142; p. 863
• Main Authors: García-Hernández, I, Gil-Saladié, D, Delgado, M, Martinell, M, Ugarte, A, Narberhaus, B
• Format: Journal Article
• Language: Spanish
• Published: Spain 01.06.1997
• Subjects: Aged; Agraphia - diagnosis; Aphasia - diagnosis; Brain - pathology; Dyslexia, Acquired - diagnosis; Hemianopsia - diagnosis; Humans; Magnetic Resonance Imaging; Middle Aged; Neuropsychological Tests; Tomography, X-Ray Computed
• ISSN: 0210-0010

Pure alexia is a syndrome characterized by the inability to read aloud in the absence of agraphia or apnasia. Three clinical cases showing this syndrome are presented. Case I had a left occipital lesion compatible with a subacute haematoma. He had problems with reading, visuo-spatial recognition, digital gnosia and memorizing texts. One year later there was considerable improvement in most of the sub-tests evaluated. There was still deficient colour naming right/left orientation and understanding of letters and words. Case 2 presented with a right homonymous hemianopia and slight left paresis. He had a small left occipital ischaemic infarct. One year later there was improvement on testing, with some deficit still in visual recognition, naming colours and memory. Case 3 presented with right homonymous hemianopia, slight right paresis and a left occipito-parietal expansive lesion. He had defective reading, choosing and naming of colours, right/left orientation and memory. On later evaluation, considerable improvement was seen. There was still colour agnosia, although less severe and mild 'laziness' of the right side. In the review of the literature, the disorder and the contributions of various authors, from Déperine in 1892 to the present day, are considered in detail.