Accessibility and possibility of elimination of breast epithelium: the theoretical possibility of preventing breast carcinoma through destruction of the epithelium of origin

Two characteristics of breast biology appear to constitute weak points in the fight against breast carcinoma. First, the epithelium from which breast carcinoma arises is of relatively easy accessibility, as it lines cavities which are in close communication with the outside. Second, the elimination...

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Bibliographic Details
Published inMedical hypotheses Vol. 33; no. 2; pp. 107 - 111
Main Author Pansera, F
Format Journal Article
LanguageEnglish
Published United States 01.10.1990
Subjects
Breast - anatomy & histology
Breast - growth & development
Breast - physiology
Breast Neoplasms - etiology
Breast Neoplasms - pathology
Breast Neoplasms - prevention & control
Epithelium - anatomy & histology
Female
Humans
Models, Biological
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Summary:Two characteristics of breast biology appear to constitute weak points in the fight against breast carcinoma. First, the epithelium from which breast carcinoma arises is of relatively easy accessibility, as it lines cavities which are in close communication with the outside. Second, the elimination of breast epithelium can be tolerated by the organism. Theoretically, breast carcinoma may be prevented by destroying breast epithelium through the injection of an agent into the ductal orifices at the nipple. This strategy appears relatively easy to perform in comparison with conventional strategies, which have not given reliable results. Therefore the possibility presented here should not be neglected.
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SourceType-Scholarly Journals-1
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ISSN:0306-9877
DOI:10.1016/0306-9877(90)90187-J