Regulation of prostatic growth, pathogenesis of prostatic adenoma and cancer

This review discusses the molecular mechanism of the regulation of prostate growth, maintenance of the prostate integrity and possible disturbances in these processes leading to the development of prostatic cancer and benign hyperplasia. The role of hormones, growth factors, oncogenes is described i...

Full description

Saved in:
Bibliographic Details
Published inVestnik Rossiĭskoĭ akademii medits︠i︡nskih nauk no. 11; p. 50
Main Authors Darenkov, A F, Evdokimov, V V, Alfimov, A E
Format Journal Article
LanguageRussian
Published Russia (Federation) 1994
Subjects
Adult
Age Factors
Aged
Aged, 80 and over
Animals
Cells, Cultured
Dogs
Growth Substances - physiology
Humans
Male
Middle Aged
Peptidyl-Dipeptidase A - physiology
Prostate - growth & development
Prostate - metabolism
Prostate - pathology
Prostatic Hyperplasia - etiology
Prostatic Hyperplasia - pathology
Prostatic Neoplasms - etiology
Prostatic Neoplasms - pathology
Renin-Angiotensin System - physiology
Online AccessGet more information

Cover

More Information
Summary:This review discusses the molecular mechanism of the regulation of prostate growth, maintenance of the prostate integrity and possible disturbances in these processes leading to the development of prostatic cancer and benign hyperplasia. The role of hormones, growth factors, oncogenes is described in more details. The participation of the angiotensin converting enzyme and renin-angiotensin systems in the regulation of polyamine synthesis in the prostate and the regulation of prostate growth is assumed.
ISSN:0869-6047