Autoimmune hemolysis caused by anti-Pr

Following an infection with mycoplasma pneumoniae, an anti-Pr-antibody developed in a hitherto healthy man, aged 41. Within a period of 5 days the antibody caused a severe autoimmune hemolytic reaction. The patient died on the fifth day after admission due to hemolysis and uremia. The autoantibody s...

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Bibliographic Details
Published inInfusionstherapie und klinische Ernährung Vol. 12; no. 4; p. 181
Main Authors Schönitzer, D, Kilga-Nogler, S, Trenkwalder, B, Lisch, H, Breier, C, Klein, G, Hintner, H
Format Journal Article
LanguageGerman
Published Switzerland 01.08.1985
Subjects
Adult
Agglutinins - analysis
Anemia, Hemolytic, Autoimmune - immunology
Antibody Specificity
Blood Grouping and Crossmatching
Cryoglobulins
Erythrocytes - immunology
Exchange Transfusion, Whole Blood
Humans
Male
Pneumonia, Mycoplasma - immunology
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Summary:Following an infection with mycoplasma pneumoniae, an anti-Pr-antibody developed in a hitherto healthy man, aged 41. Within a period of 5 days the antibody caused a severe autoimmune hemolytic reaction. The patient died on the fifth day after admission due to hemolysis and uremia. The autoantibody showed a reactivity with a broad thermal range from 4 degrees C to 37 degrees C. As an initial warning sign, the patient presented an expressed livedo reticularis. Massive wholeblood exchanges could not stop the fatal process.
ISSN:0378-0791