Transfusion malaria in promyelocytic leukemia

Five weeks after re-induction treatment and nine days after discharge from hospital, remittent fever occurred in a 34-year-old woman with promyelocytic leukaemia in full remission. She also had haemolytic anaemia and thrombocytopenia, as well as a reduced creatinine clearance. Findings on physical e...

Full description

Saved in:
Bibliographic Details
Published inDeutsche medizinische Wochenschrift Vol. 113; no. 47; p. 1841
Main Authors Shunkert, H, Handt, S, de Wit, M, Gladziwa, U, Glöckner, W M, Sieberth, H G
Format Journal Article
LanguageGerman
Published Germany 25.11.1988
Subjects
Adult
Animals
Chloroquine - therapeutic use
Drug Therapy, Combination
Erythrocyte Transfusion
Female
Humans
Leukemia, Promyelocytic, Acute - blood
Leukemia, Promyelocytic, Acute - complications
Leukemia, Promyelocytic, Acute - therapy
Malaria - blood
Malaria - drug therapy
Malaria - transmission
Plasmodium falciparum
Platelet Transfusion
Sulfadoxine - therapeutic use
Transfusion Reaction
Online AccessGet more information

Cover

More Information
Summary:Five weeks after re-induction treatment and nine days after discharge from hospital, remittent fever occurred in a 34-year-old woman with promyelocytic leukaemia in full remission. She also had haemolytic anaemia and thrombocytopenia, as well as a reduced creatinine clearance. Findings on physical examination were unremarkable, but Falciparum malaria was found in the blood smear. Infusion of erythrocyte or platelet concentrates, administered in treating the leukaemia, was the probable source of the infection. Ten days after starting the administration of chloroquine and sulfadoxine-pyrimethamine she was discharged from hospital, cured of the malaria.
ISSN:0012-0472
DOI:10.1055/s-2008-1067898