Parkinson's Disease, Dementia with Lewy Bodies, and Multiple System Atrophy as α-Synucleinopathies
Parkinson's disease (PD) is the most common neurodegenerative movement disorder (1). Neuropathologically, it is defined by nerve cell loss in the substantia nigra and the presence of Lewy bodies and Lewy neurites (2,3). In many cases, Lewy bodies are also found in the dorsal motor nucleus of th...
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Published in | Methods in molecular medicine Vol. 62; p. 33 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
2001
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Online Access | Get more information |
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Summary: | Parkinson's disease (PD) is the most common neurodegenerative movement disorder (1). Neuropathologically, it is defined by nerve cell loss in the substantia nigra and the presence of Lewy bodies and Lewy neurites (2,3). In many cases, Lewy bodies are also found in the dorsal motor nucleus of the vagus, the nucleus basalis of Meynert, the locus coeruleus, the raphe nuclei, the midbrain Edinger-Westphal nucleus, the cerebral cortex, the olfactory bulb, and some autonomic ganglia (4). |
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ISSN: | 1543-1894 |
DOI: | 10.1385/1-59259-142-6:33 |