Investigation of the Effects of Arsenic Trioxide Combined with Deslorelin on Proliferation and Apoptosis of Jurkat Cells Based on Wnt/β-Catenin Pathway

• Published in: Zhongguo shi yan xue ye xue za zhi Vol. 33; no. 3; p. 640
• Main Authors: Liu, Wei-Wan, Ren, Cui-Ai
• Format: Journal Article
• Language: Chinese
• Published: China 01.06.2025
• Subjects: Apoptosis - drug effects; Arsenic Trioxide; Arsenicals - pharmacology; beta Catenin - metabolism; Bridged Bicyclo Compounds, Heterocyclic - pharmacology; Cell Proliferation - drug effects; Humans; Jurkat Cells; Oxides - pharmacology; Wnt Signaling Pathway - drug effects; arsenic trioxide; NCTD; Jurkat cells; Wnt/β-catenin signaling pathway; apoptosis
• ISSN: 1009-2137
• DOI: 10.19746/j.cnki.issn.1009-2137.2025.03.003

To investigate the effect of Arsenic trioxide (ATO) combined with Norcantharidin (NCTD) on the proliferation and apoptosis of Jurkat cells, and to evaluate its effect on the proliferation and apoptosis of acute T-lymphoblastic leukemia (T-ALL) based on the Wnt/β-catenin signaling pathway. Jurkat cel...