Full-field stimulus threshold testing for evaluation of the retinal function in patients with inherited retinal dystrophy

• Published in: Chung-hua yen k'o tsa chih Vol. 58; no. 12; p. 1039
• Main Authors: Li, H, Zou, X, Han, X X, Sui, R F
• Format: Journal Article
• Language: Chinese
• Published: China 11.12.2022
• ISSN: 0412-4081
• DOI: 10.3760/cma.j.cn112142-20220417-00184

To analyze the characteristics of full-field stimulus thresholds (FST) in patients with middle-and late-stage inherited retinal dystrophy (IRD), and to explore the feasibility of the FST test in evaluating the retinal function for IRD patients. It was a retrospective case series study. Twenty-eight patients with IRD whose full-field electroretinogram (ERG) results showed no electrical activity (20 patients) or a serious decrease in electrical activity (8 patients) were enrolled, including 17 males and 11 females, with a median age of 32 years. Ten normal controls were also enrolled. All eyes had a measurement of best corrected visual acuity (BCVA) and an ERG test. FST stimulated by red, blue and white lights were examined with an electrophysiological instrument. The decimal value of BCVA was converted to logarithm of the minimum angle of resolution. Data of the better eye of each participant were used for statistical analysis. Independent sample -test was used to analyze the difference in FST among patients.