A Case of Heterochronic Cervical Esophageal Cancer with a Subcutaneous Abscess Showing a Complete Response to Chemoradiation Therapy

We report a case of heterochronic cervical esophageal cancer with a subcutaneous abscess successfully treated using chemoradiation. A 68-year-old man underwent esophagectomy for middle thoracic esophageal cancer 13 years ago. In April 2015, upper gastrointestinal endoscopy revealed advanced residual...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 43; no. 12; p. 2004
Main Authors Nishiyama, Mitsuo, Takeda, Shigeru, Kanekiyo, Shinsuke, Iida, Michihisa, Kitahara, Masahiro, Tokumitsu, Yukio, Tomochika, Shinobu, Tokuhisa, Yoshihiro, Sakamoto, Kasuhiko, Suzuki, Nobuakl, Ueno, Tomio, Yamamoto, Shigeru, Yoshino, Shigefumi, Hazama, Shouichi, Nagano, Hiroaki
Format Journal Article
LanguageJapanese
Published Japan 01.11.2016
Subjects
Abscess - etiology
Aged
Antineoplastic Agents, Phytogenic - therapeutic use
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Chemoradiotherapy
Cisplatin - administration & dosage
Esophageal Neoplasms - complications
Esophageal Neoplasms - therapy
Esophagectomy
Fluorouracil - administration & dosage
Humans
Male
Paclitaxel - therapeutic use
Stomach Neoplasms - complications
Stomach Neoplasms - therapy
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Summary:We report a case of heterochronic cervical esophageal cancer with a subcutaneous abscess successfully treated using chemoradiation. A 68-year-old man underwent esophagectomy for middle thoracic esophageal cancer 13 years ago. In April 2015, upper gastrointestinal endoscopy revealed advanced residual cervical esophageal cancer. Enhanced CT showed a massive tumor with a subcutaneous abscess, and the tumor had invaded the left internal jugular vein and the 8th cervical spine. We firstly performed abscess drainage and administered antibiotics. After the inflammation decreased, we started chemora- diation. Chemotherapy consisted of 70mg/m / 2 cisplatin(day 1)and 700 mg/m2 5-FU(days 1-5)combined with almost 60 Gy radiotherapy(1.8 Gy/day, 5 days/week, days 1-49). We administered cisplatin and 5-FU only once because renal dys- function occurred. Consequently, we changed the regimen to weekly 100mg/m2 paclitaxel administration(day 1). After 2 months, a clinical complete response(CR)was obtained and we stopped chemotherapy. Eight months after chemotherapy cessation, the patient shows no sign of recurrence. These results suggest that chemoradiation is an effective treatment for cervical esophageal cancer with a subcutaneous abscess.
ISSN:0385-0684