Activated brain areas during simple and complex mental calculation--a functional MRI study

Functional magnetic resonance imaging (fMRI) was used to study the activated brain areas of human during simple and complex digital calculation, and to investigate the role of cortical and subcortical structures involved in the mental calculation. Sixteen right-handed healthy volunteers performed me...

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Bibliographic Details
Published inSheng li hsüeh pao Vol. 60; no. 4; p. 504
Main Authors Zhang, Zeng-Qiang, Shu, Si-Yun, Liu, Song-Hao, Guo, Zhou-Yi, Wu, Yong-Ming, Bao, Xin-Ming, Zheng, Jin-Long, Ma, Han-Zhang
Format Journal Article
LanguageChinese
Published China 25.08.2008
Subjects
Brain - physiology
Brain Mapping
Humans
Magnetic Resonance Imaging
Parietal Lobe - physiology
Thinking - physiology
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Summary:Functional magnetic resonance imaging (fMRI) was used to study the activated brain areas of human during simple and complex digital calculation, and to investigate the role of cortical and subcortical structures involved in the mental calculation. Sixteen right-handed healthy volunteers performed mental calculation of simple and complex addition/subtraction respectively, while the fMRI data were recorded by a Seimens 1.5 T MR machine. Block-design was used in the tasks. Two calculation tasks and one base-line tasks were performed for the block-design. Simple calculation task was single-digit addition and subtraction, while the complex was multi-digit addition and subtraction. The base-line task was to tell whether the two numbers were the same in every trial. Statistical parametric mapping (SPM99) was employed to process data and localize functional areas. We compared the average activation intensity of each activated brain regions in the same calculation task and the activation intensity of the same regions
ISSN:0371-0874