The clinical value of urinary antigen detection of Legionella pneumonia

To investigate the clinical value of urinary antigen detection of Legionella, and to describe the clinical characteristics of Legionella pneumonia. Patients with suspected Legionella pneumonia were enrolled from the Respiratory departments of 3 tertiary hospitals in Shenyang during May 2011 to Novem...

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Published inZhonghua jiehe he huxi zazhi Vol. 38; no. 1; p. 29
Main Authors Jiang, Luxi, Chen, Yu, Xia, Shuyue, Ma, Jiangwei, Zhao, Hongwen, Lu, Ye, Tao, Sixu, Zhao, Li
Format Journal Article
LanguageChinese
Published China 01.01.2015
Subjects
Antibodies, Bacterial
Antigens, Bacterial - urine
Fluoroquinolones
Humans
Legionella - isolation & purification
Legionnaires' Disease - diagnosis
Legionnaires' Disease - urine
Pleural Effusion
Pneumonia - diagnosis
Pneumonia - urine
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Summary:To investigate the clinical value of urinary antigen detection of Legionella, and to describe the clinical characteristics of Legionella pneumonia. Patients with suspected Legionella pneumonia were enrolled from the Respiratory departments of 3 tertiary hospitals in Shenyang during May 2011 to November 2013. Urinary Legionella antigen was detected for all the enrolled patients. Bacterial culture, polymerase chain reaction (PCR) for Legionella, and double Legionella antibody detection in sera were performed for each patient whose urinary antigen was positive. Patients confirmed to have Legionella pneumonia were pooled and analyzed. Totally 13 cases presenting with pneumonia were positive for Legionella by the urinary antigen method, and in one of them Legionella strain was isolated from the secretion of lower respiratory tract. PCR detection was performed in 8 patients, and 4 of them were positive. Legionella antibody detection was performed in 12 patients, and 7 of them were positive. Nine patients had a hist
ISSN:1001-0939