Strategy for Unresectable Pancreatic Cancer with Stenosis of the Duodenum - A Case Report

Unresectable(UR)pancreatic cancer often causes duodenal obstruction. Case 1: A 58-year-old man was diagnosed with UR pancreatic cancer with obstruction of the 3rd duodenal portion. A duodenum 2nd portion jejunum bypass was performed, and FOLFIRINOX was introduced and continued over 6 months. Case 2:...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 43; no. 12; p. 1656
Main Authors Komagome, Masahiko, Ninomiya, Riki, Nakazawa, Akiko, Mitsui, Tetsuya, Maki, Akira, Ozawa, Fumiaki, Beck, Yoshifumi
Format Journal Article
LanguageJapanese
Published Japan 01.11.2016
Subjects
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Duodenal Obstruction - etiology
Humans
Male
Middle Aged
Pancreatic Neoplasms - complications
Pancreatic Neoplasms - diagnostic imaging
Pancreatic Neoplasms - drug therapy
Pancreatic Neoplasms - surgery
Tomography, X-Ray Computed
Treatment Outcome
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Summary:Unresectable(UR)pancreatic cancer often causes duodenal obstruction. Case 1: A 58-year-old man was diagnosed with UR pancreatic cancer with obstruction of the 3rd duodenal portion. A duodenum 2nd portion jejunum bypass was performed, and FOLFIRINOX was introduced and continued over 6 months. Case 2: A 74-year-old man was diagnosed with UR pancreatic cancer with obstruction of the duodenum near the Treitz ligament. A duodenum 3rd portion jejunum bypass was performed, and gemcitabine plus nab-paclitaxel was introduced. After 8 courses of GN, adjuvant surgery was performed. Both patients resumed oral intake within a few days after bypass, their performance statuses(PS)were improved, and their body weights increased. Because a duodenal jejunum bypass is more physiological than a gastro-jejunum bypass and duodenal stent, stable ingestion is enabled, and they are stable enough for early initiation of chemotherapy.
ISSN:0385-0684