Evaluating Dengue Virus Pathogenesis in Mice and Humans by Histological and Immunohistochemistry Approaches
The analysis of dengue virus (DENV) infected tissues in mice experimental model and in human biopsies/autopsies may support the pathogenesis studies. Through such models, it is possible to investigate possible histopathological changes caused by the infection and detections of different targets of i...
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Published in | Methods in molecular biology (Clifton, N.J.) Vol. 2409; p. 259 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
2022
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Subjects | |
Online Access | Get more information |
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Summary: | The analysis of dengue virus (DENV) infected tissues in mice experimental model and in human biopsies/autopsies may support the pathogenesis studies. Through such models, it is possible to investigate possible histopathological changes caused by the infection and detections of different targets of interest, such as viral antigens, immune cells, and cytokines. In this chapter, we showed a brief review of how histological and immunohistochemistry approaches may improve the knowledge in this field. |
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ISSN: | 1940-6029 |
DOI: | 10.1007/978-1-0716-1879-0_18 |